تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
The cytotoxic effect of PM 701 and its fractions on cell proliferation of breast cancer cells, MCF7
The cytotoxic effect of PM 701 and its fractions on cell proliferation of breast cancer cells, MCF7
 
الموضوع : علوم الأحياء 
لغة الوثيقة : الانجليزية 
المستخلص : Breast cancer is the most common malignancy in the world among women. Many therapies have been designed to treat this disease. Mamectomy, chemotherapy and radiotherapy are still the main therapies of breast cancer. However, the results were unsatisfactory and still far from the ideal treatment. PM 701 is a natural product, has anticancer activity. The bioactive fraction PMF and subfraction PMFK had been isolated from PM 701. PM 701 and its fractions were proved to have a cytotoxic properties against different cancer cell lines. This study is directed for the further examination of lyophilized PM 701 and its active fractions on the growth of breast cancer cells (MCF-7). PM 701, PMF or PMFK were adding to the cultural medium, where MCF-7 is incubated. PM 701, PMF or PMFK were able to inhibit significantly the proliferation of MCF-7 cells. These new agents were proved to induce apoptosis of the breast cancer cells; through its direct effect on the nuclei. 
ردمد : 2150427X 
اسم الدورية : American Journal of Drug Discovery and Development 
المجلد : 1 
العدد : 3 
سنة النشر : 1432 هـ
2011 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Tuesday, June 5, 2012 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
فاتن خورشيدKhorshid, Faten باحثدكتوراهfatenkhorshid@yahoo.com

الملفات

اسم الملفالنوعالوصف
 33492.pdf pdfAbstract

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